NIH Guide Notices

Dear Colleagues:

Below is a summary of a recent NIH Guide Notices. Please review the notices and forward them to faculty, researchers and staff, as appropriate. Questions regarding the notices should be directed to your Federal Contract and Grant Officer.

This Notice informs the extramural research community of planned changes to the Research Performance Progress Report (RPPR) instructions to address the NIH Data Management and Sharing Policy. The updated NIH RPPR Instruction Guide will be posted to the Research Performance Progress Report (RPPR) page. NIH plans to implement the new questions for RPPRs submitted on or after October 1, 2024. 

Please review the notice for additional information.

Effective for application due dates on or after June 12, 2024, NIAID will raise the maximum salary and research support provided on NIAID K99 awards, NIAID K25 awards and NIAID K01 awards through the Parent NOFO or any reissue.

NIAID K99, K25, and K01 award levels will be:

Salary Support
Up to $100,000 plus fringe benefits per year (increased from $75,000). As always, salary must be consistent with effort committed to the award and institutional compensation policies.

Research Support
Up to $50,000 per year (increased from $25,000 for K99 and K01, increased from $20,000 for K25).

R00 Years for Support

Effective for application dues dates on or after June 12, 2024, NIAID will increase the support period for the R00 phase through the Parent NOFO or any reissue. The K99/R00 award will provide up to 5 years of support in two phases. The K99 phase will provide support for up to 2 years of mentored postdoctoral career development. The R00 phase will provide up to 3 years (increased from 2 years) of independent research support.

Please review the notice for additional information.

Beginning with applications submitted for receipt dates on or after September 25, 2024, NIAID will limit the total number of predoctoral and/or postdoctoral training slots to a maximum of 8 trainee slots/training grant in any given year for the Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grant (Parent T32)  or any reissue of this funding opportunity as an operational accommodation due to budgetary constraints. This is for competing and non-competing T32 grants. 
Current NIAID T32 grantees with 10 or more than 10 trainee slots/year will need to reduce their number of slots by not reappointing vacated slots until the 8-slot limit is reached and maintained. Furthermore, for competing renewal (T2) applications, the maximum increase in the number of trainee slots from the past non-competing (T5) year will be 2, up to the maximum 8-slot limit.

Updates to NIH Training Grant Applications – Registration Open for June 5, 2024 Webinar


The NIH Institutional Training Grant Program application is undergoing changes that take effect for submissions due on or after January 25, 2025. Make plans to participate in an informative and engaging webinar, hosted by NIH on June 5 at 1:00 p.m. ET.

These upcoming changes will:

  • Move and make the Recruitment Plan to Enhance Diversity a separate attachment within the PHS 398 Research Training Program Plan Form,
  • Update Institutional Training grant data tables to reduce the burden on the research community and promote consistent information collection across training programs,
  • Define mentor training expectations in parent T32 Notices of Funding Opportunity (NOFOs), and
  • Include “Training in the Responsible Conduct of Research” and the “Recruitment Plan to Enhance Diversity” as items that contribute to the overall impact score.

Webinar: Updates to NIH Training Grant Applications

Please review the notice for additional information.

Nancy Lewis
Senior Director, Sponsored Projects Administration
Office of Research
University of California, Irvine
160 Aldrich Hall
Irvine, CA 92697-7600
Ph-(949) 824-2897

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