ZOT IRB Updates: Logo and Protocol Narratives!

Institutional Review Board (IRB)

August 22, 2025

Launches on
September 15, 2025!!

LOGO

Based on popular choice, and with a few extra touches, here is our version of Peter the Anteater. The above logo will appear on our IRB and hSCRO applications. Thank you to all of you who voted!

PROTOCOL TEMPLATES FINALIZED

Our templates for Protocol Narratives and Principal Investigator (PI) Worksheets have been finalized and are available in the HRP Toolkit. Please consider creating your templates NOW as part of preparing for a new submission in ZOT IRB on or after September 15, 2025.

As part of ZOT IRB, a protocol submission includes the electronic application, a Protocol Narrative (as applicable), Principal Investigator (PI) Worksheets (as applicable), and other research documents (e.g., recruitment materials, consent forms). PI Worksheets are to be completed based on special populations and considerations in human research that either require regulatory documentation and / or input from the PI to ensure human research protections.

We will provide more information on the HRP Toolkit shortly. For now, we encourage you to take a look at the HRP Toolkit to familiarize yourself with the material.

PROTOCOL TRANSCRIPTION

For current IRB approved protocols, a PDF was generated of the KRP protocol (KRP PDF) and was attached to the protocol in ZOT IRB. The information from the KRP PDF must be transcribed (i.e., cut and paste) into the Protocol Narrative and / or applicable PI Worksheets according to the table below.

	Greater than minimal risk protocols & FDA regulated protocols	Non-FDA regulated protocols, including exempt research that requires IRB review	Protocols closed to enrollment, in follow-up or data analysis only
Minor (non personnel) modification. Transcribe only the sections of the protocol that require changes.	YES*	YES*	YES*
Major modification. Transcribe the entire protocol.	YES	YES	YES
Renewal. Transcribe the entire protocol.	YES	YES+	NO

*While the goal is to try to minimize burden to our UCI Research Community, the IRB and HRP Staff reserve the right to use discretion as to when they believe a complete Protocol Narrative should be included in the submission for the purpose of facilitating the IRB review process.

+Should the transcription cause an administrative hardship on the study team, at their discretion the IRB and HRP Staff may issue a one-time exception to transcribe the protocol.

CONTINUOUS IMPROVEMENT

Feel free to share your feedback as you use ZOT IRB and the HRP Toolkit. We anticipate continuous improvement and we need input and feedback from our UCI Researchers, the IRB and our HRP. Email feedback to the IRB at IRB@UCI.edu or reach out to Beverley Alberola or Jessica Sheldon directly.

THANK YOU!

We appreciate our UCI Research Community, our IRB Chairs, IRB Members, Human Research Protections (HRP) and Office of Research Colleagues for their patience and support during this important and complex transition. We look forward to working together to make ZOT IRB a success at UCI for (many) years to come!!

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