Human Stem Cell Oversight Committee (hSCRO)

ZOT hSCRO Updates: Logo and Protocol Narratives!

August 26, 2025

Launches on
September 15, 2025!!

LOGO

Based on popular choice, and with a few extra touches, here is our version of Peter the Anteater. The above logo will appear on our IRB and hSCRO applications. Thank you to all of you who voted!

PROTOCOL TEMPLATES FINALIZED

Our template for Protocol Narratives has been finalized and is available on the hSCRO Forms & Guidance webpage. Please consider creating your template NOW as part of preparing for a new submission in ZOT hSCRO on or after September 15, 2025.

As part of ZOT hSCRO, a protocol submission includes the electronic application, a Protocol Narrative and other research documents (e.g., provenance documents, consent forms).

PROTOCOL TRANSCRIPTION

For current hSCRO approved protocols, a PDF was generated of the KRP protocol (KRP PDF) and was attached to the protocol in ZOT hSCRO. The information from the KRP PDF must be transcribed (i.e., cut and paste) by the study team into the Protocol Narrative as applicable according to the table below.

Type of Transaction	Transcription Process*
Minor Personnel only amendments	Does not require transcription. ZOT hSCRO has a separate section for personnel changes.
Minor (non personnel) amendments (such as addition of registered cell lines or cell lines previously verified by hSCRO; deletion of cell lines and activities that do not significantly affect the assessment of ethical and social issues; activities that do not significantly change study design or aims).	Transcribe only the sections of the protocol that require changes.^*
Major amendment (such as changes significantly affecting ethical and social issues, aims or study design; addition of new cell lines that are not registered or previously approved by hSCRO).	Transcribe the entire protocol.⁺
Renewal	Transcribe the entire protocol. ⁺

* While the goal is to try to minimize burden to our UCI Research Community, the hSCRO and HRP Staff reserve the right to use discretion as to when they believe a complete Protocol Narrative should be included in the submission for the purpose of facilitating the hSCRO review process.

+ Should the transcription cause an administrative hardship on the study team, at their discretion the hSCRO and HRP Staff may issue a one-time exception to transcribe the protocol.

CONTINUOUS IMPROVEMENT

Feel free to share your feedback as you use ZOT hSCRO. We anticipate continuous improvement and we need input and feedback from our UCI Researchers, the hSCRO and our HRP. Email feedback to the hSCRO at hscro@uci.edu or reach out to Beverley Alberola or Jessica Sheldon directly.

THANK YOU!

We appreciate our UCI Research Community, our hSCRO Chairs, hSCRO Members, Human Research Protections (HRP) and Office of Research Colleagues for their patience and support during this important and complex transition. We look forward to working together to make ZOT hSCRO a success at UCI for (many) years to come!!

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Send a blank email to: or-hscro+subscribe@uci.edu