NIH Guide Notice Updates

Dear Colleagues:
Below is a summary of a recent NIH Guide Notice. Please review the notice and forward it to faculty, researchers and staff, as appropriate. Questions regarding the notices should be directed to your Federal Contract and Grant Officer.
NIH policy requires any applicant requesting research support of $500,000 or more in direct costs in a single budget period to obtain approval to submit the application from an Institute or Center at least six weeks before the intended submission date. This policy applies to an unsolicited application, whether it is new (type 1), a competing renewal (type 2), a competing revision (type 3), or a resubmission (A1).
As part of new budget control measures, NIA’s implementation of this policy has been revised in the following ways (changes in bold italics; see NIA guidance for ARAs):
NIA will make competing large awards based on NIA Funding Line Policy for a given fiscal year. To enable NIA program divisions to consider research project applications with large budgets as early as possible in the budget and program planning process, investigators must seek approval to submit their applications in the form of an Awaiting Receipt of Application (ARA).
 Investigators are strongly encouraged to contact an NIA Program Officer (PO) at least 10 weeks prior to the ARA submission due date to obtain assistance in submitting an ARA request. A PO can be identified by reaching out to the NIA Scientific/Research Contact listed at the end of Section VII of the Notice of Funding Opportunity (NOFO). The PO will discuss the project, provide access to the ARA Request Form, and offer further guidance. Please note that submitting an ARA request does not ensure its approval; it only ensures the request will be reviewed internally at NIA.
Failure to seek ARA approval for a large budget grant application prior to submission will result in the application not being accepted for review and a delay in consideration until the next ARA due date.
Please review the guide notice for additional information.
Effective with new (Type 1) K01, K25, and K99 applications due on June 12, 2024, and subsequently, several NIH Institutes and Centers (ICs) will increase the contribution toward the K awardee’s salary support for the requested effort (e.g., nine  person months, equivalent to 75% full-time professional effort devoted to research and career development) to a base level of $100,000.
Please review the guide notice for additional information.
This notice announces updates to the NIH Institutional Training Program applications and required training data tables. These changes take effect starting with submissions for due dates on or after January 25, 2025.  The overall goal of these changes is to:
  • Reduce applicant and reviewer burden. 
  • Further support the development of a biomedical research workforce that will benefit from the full range of perspectives, experiences and backgrounds needed to advance discovery.
  • Align SF424 with updates with relevant NIH training grant NOFOs and requirements.
Please review the guide notice for additional information.
Nancy Lewis
Senior Director, Sponsored Projects Administration
Office of Research
University of California, Irvine
160 Aldrich Hall
Irvine, CA 92697-7600
Ph-(949) 824-2897

Scroll to Top