NIH Guide Notices for 03-27-2026 (The NIH Guide TOC)

Dear Colleagues:

The National Institutes of Health (NIH) issued the following policy notices last week. If you have any questions, please contact your Federal Contracts and Grants Officer (https://research.uci.edu/about-or/contact/staff-by-dept-assignment/) or me at warnerj@uci.edu.

“This update incorporates new and modified requirements, clarifies certain policies, and implements changes in statutes, regulations, and policies that have been implemented through appropriate legal and/or policy processes since the previous version of the NIHGPS dated April 2024.”

Please also review NIH’s significant changes table for additional details: https://grants.nih.gov/grants/policy/nihgps/Significant_Changes_NIHGPS.pdf.

“Effective June 1, 2026, all prime recipients are required to obtain NIH prior approval when adding a new domestic subaward to a project post-award, when the arrangement was not originally a part of the peer-reviewed and approved application.”

Regards,

Jeff Warner

Senior Director, Sponsored Projects

Office of Research

University of California Irvine

warnerj@uci.edu

949-824-7654

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